Research

Advances in medical research in recent years have produced the safest blood supply in the nation's history.

Bonfils Blood Center's research department is dedicated to the study of blood and transfusion medicine and the treatment, prevention and cure of blood-related illnesses. Our research team is currently studying several issues related to hematology and transfusion medicine.

Bonfils Blood Center's Research Staff

Current research projects include:

TRALI

One of the keystone projects in Bonfils’ research laboratories is the study of transfusion-related acute lung injury (TRALI).  Improved donor screening, enhanced testing, changes in processing and progress in the practice of transfusion medicine have led to a decrease in the risks for many adverse events related to blood transfusion.  However, some reactions have become more apparent and TRALI is one such reaction.

Bonfils’ researchers’ goal, under the direction of Associate Medical Director Daniel R. Ambruso, MD is to identify the causes of TRALI through clinical case studies.  This potentially serious complication of blood transfusion typically presents itself within six hours after transfusion, with most cases presenting within one to two hours, is treatable when diagnosed early.  Research will expand Bonfils’ knowledge and understanding of the basic mechanisms and clinical manifestations of TRALI and will enhance the safety of blood transfusion and the quality of patient care.  Bonfils researchers are close to developing a TRALI identification test kit that will be made available to attending physicians and hospitals.